Botanical Cube Inc. is one of the most professional manufacturers and suppliers of pyrroloquinoline quinone powder in China, featured by quality products and good price. Please rest assured to wholesale bulk discount pyrroloquinoline quinone powder from our factory.
High-Purity PQQ Powder – Traceable, Certified, Ready for Bulk Supply
Pyrroloquinoline Quinone (PQQ) Powder is widely recognized for its antioxidant potential and ability to support cellular energy. Unlike many suppliers who focus solely on mass production, Botanical Cube emphasizes full production transparency, batch-to-batch consistency, and proactive technical support. Each batch of our PQQ powder is produced under cGMP-certified conditions, rigorously tested, and fully traceable from raw material to finished product. This approach ensures that our partners receive not just a high-purity ingredient, but also confidence in stability, compliance, and scalable supply, making us a preferred choice for dietary supplements, functional beverages, and cosmetic manufacturers worldwide.
PQQ Powder – Focused Product Insights
|
Feature |
Details |
|
Appearance |
Light yellow crystalline powder |
|
Purity |
≥99% (HPLC tested) |
|
Solubility |
Water-soluble for easy integration into formulations |
|
CAS Number |
72909-34-3 |
|
Molecular Formula |
C14H6N2O8 |
|
Packaging & Supply |
Bulk supply, flexible OEM/Private label options |
|
Shelf Life |
Optimized for long-term storage and stability |
Why Our Partners Value PQQ Powder?
1. Optimized for Formulation – Designed for smooth incorporation into beverages, dietary supplements, and cosmetic products without altering product texture or appearance.
2. Consistent Performance – Maintains activity over time, reducing formulation variability and ensuring predictable results.
3. Flexible Supply Options – Suitable for both small-scale product trials and large-scale commercial production.
4. Application Support – Our team can advise on integration strategies, helping clients shorten development cycles and reduce trial-and-error.
|
|
Abbreviation |
PQQ |
Full name |
Pyrroloquinolinequinone disodium salt |
|
CAS No. |
122628-50-6 |
Molecular weight |
374.170 |
|
|
Molecular formula |
C14H4N2Na2O8 |
Boiling Point |
1018.6ºC at 760mmHg |

COA
| Physical and Chemical Property | |||
| Appearance | Red to reddish-brown powder | Conforms | Visual |
| Loss on Drying | ≤12.0g/100g | 8.20g/100g | Fischer titration |
| Identification | Shall meet the control article | Conforms | IR |
| Assay(as dry) | ≥99% | 99.50% | HPLC |
| Purity | ≥99% | 99.90% | HPLC |
| Residue Analysis | |||
| Alcohol residue | ≤3000mg/kg | Conforms | GC |
| Pb | ≤1.00mg/kg | Conforms | ICP-MS |
| As | ≤1.00mg/kg | Conforms | ICP-MS |
| Cd | ≤0.50mg/kg | Conforms | ICP-MS |
| Hg | ≤0.10mg/kg | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤1000cfu/g | 50cfu/g |
GB4789.2 |
| Yeast & Mold | ≤100cfu/g | 10cfu/g |
GB4789.15 |
| E.Coli. | Negative/10g | Conforms |
GB4789.38 |
| Salmonella | Negative/10g | Conforms |
GB4789.4 |
| Staphylococcus aureus | Negative/10g | Conforms |
GB4789.10 |
Pyrroloquinoline Quinone (PQQ) Powder – Precision Production
Different from standard suppliers, our PQQ Powder is uniform, application-ready, and consistently high-yield, ideal for supplements, beverages, and cosmetics.
Production Process:
Step 1 – Raw Material Verification 🔬
Only ≥99% pure starting compounds with moisture <1%
Batch HPLC testing ensures consistent quality
Step 2 – Controlled Reaction ⚗️
Reaction temperature: 25–30°C, pH 6–7
Duration: 8–10 hours, yield >95%
Precise control reduces batch variability compared to competitors
Step 3 – Multi-Stage Purification 💧
Impurities removed to <0.5%
Produces water-soluble intermediates, ready for crystallization
Step 4 – Slow Crystallization ❄️
Cooling from 30°C → 5°C over 6 hours
Forms uniform crystals for enhanced solubility and stability
Step 5 – Vacuum Drying & Sieving 🌬️
Dried at 40–45°C, moisture <2%
Sieved to mesh 80–100, creating fine, free-flowing powder
Step 6 – Final QC & Packaging 📦
HPLC, microbial, and heavy metal testing
Packaged in moisture-proof bags/drums
Ready for bulk supply or OEM/Private Label

Why Our PQQ Powder Stands Out?
1. Application-Ready Crystals – Direct integration into supplements, drinks, and cosmetics
2. High Yield & Consistency – >95% yield, minimized waste
3. Flexible Supply – Supports both trials and large-scale production
4.Technical Support – Advice on formulation speeds up product development
Common Applications and Recommended Dosages
Applications:
1. Dietary Supplements – Support mitochondrial function, cognitive health, and energy metabolism.
2. Functional Foods and Beverages – Added to energy drinks and fortified foods for increased vitality.
3. Cosmetics and Skincare – Uses its antioxidant properties to reduce oxidative stress.
4. Pharmaceuticals – Researched for neuroprotective and cardiovascular benefits.
Recommended Dosages:
1. General Health and Energy Support: 10-20 mg/day
2. Cognitive Function and Anti-Aging: 20-40 mg/day
3. Clinical Uses (Under Study): Up to 80 mg/day (Under Medical Supervision)
FAQs
Q1: How stable is PQQ in supplements or beverages?
A: Studies show PQQ is stable at room temperature for at least 12 months in dry powder form; in liquids, stability depends on pH and packaging - recommend pH 6–7, airtight light-resistant containers.
Q2: What is the typical bioavailability of PQQ?
A: Clinical research indicates oral bioavailability around 20–25%, with plasma peaks observed 2–3 hours after ingestion.
Q3: Can PQQ be combined with other antioxidants or mitochondria-supporting ingredients?
A: Yes, PQQ is often combined with CoQ10, NADH, or resveratrol without reducing activity. Compatibility studies show no significant loss of PQQ activity.
Q4: What is the recommended daily intake for adults?
A: Most clinical studies use 10–20 mg/day; doses up to 20 mg/day are generally considered safe for healthy adults.
Q5: Is PQQ safe for use in functional beverages or cosmetic formulations?
A: Yes, GRAS status and multiple safety studies support safe use up to recommended dosages, but final formulation should comply with local regulations.
Q6: How should PQQ powder be stored to maintain activity?
A: Store in cool, dry, airtight containers, away from light; moisture <3% and temperature <25°C ensures long-term stability.
Work with a Supplier Who Understands PQQ
As a reliable PQQ Powder supplier, we combine technical expertise, consistent batch quality, and formulation-ready crystals to support your supplements, beverages, and cosmetic products. Our process-focused approach ensures predictable performance, scalable supply, and practical guidance for your business. Contact us today at sales@botanicalcube.com to discuss your PQQ needs and secure a partner who knows both the science and the market.
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