Botanical Cube Inc. is one of the most professional manufacturers and suppliers of wheat germ extract spermidine powder in China, featured by quality products and good price. Please rest assured to wholesale bulk discount wheat germ extract spermidine powder from our factory.
What is spermidine?
Spermidine is a naturally occurring polyamine found in all living organisms. It plays an important role in numerous cellular functions, such as maintaining DNA stability, copying DNA into RNA, and preventing cell death. In addition, spermidine has been found to reduce the development of many age-related health conditions, including cardiovascular diseases.
During the aging process, the levels of spermidine decrease, resulting in the development of age-related conditions. Therefore, maintaining optimal levels of spermidine throughout life has been suggested to reduce the development of diseases and increase longevity.
In humans, spermidine is synthesized from its precursor putrescine and is a key component in the production of spermine, another essential polyamine. It supports cellular health, growth, and maintenance and is essential for overall biological processes.
One of the most notable functions of spermidine is its role as a potent activator of autophagy – a natural cellular process that removes damaged components and promotes cell renewal. By stimulating autophagy, spermidine helps restore cellular activity and extend lifespan. Recent studies suggest that increasing dietary spermidine intake may reduce all-cause mortality, particularly by supporting cardiovascular health.
Where does spermidine come from?
Besides the body's own production of spermidine, spermidine-rich foods and the gut microbiome are considered the most important sources. Polyamines like spermidine can be found in all kinds of food in a wide range of concentrations. A well-known plant source is wheat germ.
Currently, there are no official recommendations for the daily intake of spermidine, but clinical studies suggest that 1-6 mg per day is an optimal supplement . With increasing age, the body produces less and less spermidine , which is why it makes sense to take it as a food supplement.
The production process of Wheat Germ Extract spermidine
1. Harvesting: Wheat kernels are harvested from mature wheat plants.
2. Cleaning: The wheat kernels are cleaned to remove debris and other impurities.
3. Grinding: The cleaned wheat kernels are ground to separate the germ from the rest of the kernel.
4. Extraction: The wheat germ is then cold-pressed to extract its oil, which is rich in beneficial nutrients.
5. Purification: The oil is then purified using various techniques such as filtration or centrifugation to remove any impurities and increase the purity of the extract.
6. Standardization: The purified wheat germ extract is standardized to contain a specific amount of active compounds, such as tocopherols and polyphenols, to ensure that it is pure and consistent in terms of potency.
7. Drying: The wheat germ powder is then dried to remove any remaining moisture and ensure that it is stable for storage and use in health and wellness products.
8. Quality control: The final wheat germ powder is then tested to ensure that it meets specific quality standards, including purity, potency, and safety. The extract is then packaged and shipped to customers for use in a variety of health and wellness products.
COA
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Botanical Source: |
Triticum aestivum |
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Part used: |
Germ |
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Specification: |
1% |
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Active Ingredient: |
Spermidine |
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Appearance: |
Yellow |
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Flavor & Odor: |
The unique flavor taste of wheat germ |
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Physical: |
Fine Powder |
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Loss on Drying: |
≤5.0% |
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Ash: |
≤5.0% |
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Test Method: |
GC |
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Heavy Metal: |
≤10mg/kg |
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Pb |
≤3mg/kg |
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As |
≤1mg/kg |
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Hg |
≤0.1mg/kg |
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Cd |
≤1mg/kg |
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Aerobic Bacterial Count: |
≤1,000CFU/g |
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Yeast & Mold: |
≤100cfu/g |
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Staphylococcus aureus: |
Negative |
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E.Coli: |
Negative |
Which food has the highest content of spermidine?
There are many plant-derived foods with moderate to high levels of Spermidine; these include Soya beans, Wheatgerm, Vegetables (peas and mushrooms are both excellent sources) as well as cruciferous veg such as cauliflower or broccoli, Cheese (particularly cheddar, brie, parmesan, and gouda), Fruits (mangos and bananas particularly so).
How does spermidine work?
Spermidine has been characterized as a natural autophagy inducer. Autophagy is a process by which cells get rid of parts that are no longer needed or don't work right, helping cells stay healthy and promoting longevity. Spermidine has been shown to block several enzymes that negatively control autophagy and may be as powerful as rapamycin, an FDA-approved immunosuppressant with strong autophagy-stimulating effects.
Benefits of Spermidine
- Anti-Aging Compounds
Spermidine is a polyamine found in the body which produces the anti-aging process of autophagy. Levels naturally decrease as we age. Polyamine levels can be increased by including spermidine-rich foods or supplements.
- Improves Memory Loss
Spermidine helps dissolve amyloid-beta proteins through autophagy. These protein plaques can build up in the brain and are thought to be related to memory loss.
- Reduce the Risk of Cancer
Studies have suggested that an increase in the nutritional uptake of the natural polyamine spermidine may be associated with reduced overall cancer-specific mortality.
- Triggers Autophagy
Spermidine induces autophagy, the process of cellular rejuvenation. Autophagy regulates cellular metabolism and balances nutrients during cell stress.
- Assists in Cellular Growth
Spermidine polyamines can bind to many different types of molecules supporting processes like cell growth. Spermidine also appears to function as a factor during cell division, which is important for healthy tissue growth and function.
- Decrease Oxidative Stress
Spermidine induced autophagy helps cells reuse their old or damaged organelles to attain cellular renewal. This limits inflammation and oxidative stress, the main culprits involved in aging and related diseases.
- Minimize Heart Disease
Aging leads to the stiffening of the heart muscles. This can potentially increase cardiovascular system failure. Spermidine may prevent that by helping increase the elasticity of the heart muscle.
Supplements containing spermidine
The majority of spermidine supplements on the market are spermidine-rich wheat germ extract. The main ingredient in it is concentrated wheat germ extract, with a branded spermidine ingredient.We provide spermidine tablets and spermidine capsules are available.
Spermidine Dosage
Spermidine is new to the market, and not recommended dose for the time being. One supplement has a max daily intake of 2 grams of spermidine extract, equivalent to 12 mg pure spermidine a day.
Why choose Botanical Cube's Wheat Germ Extract spermidine
1. High-quality sourcing: We source our Wheat Germ Powder from trusted suppliers who use sustainable and environmentally friendly farming practices. This ensures that our Wheat Germ Powder is of the highest quality, free from contaminants and impurities.
2. Standardized potency: Our Wheat Germ Extract is standardized to contain a specific amount of active compounds, such as tocopherols and polyphenols, ensuring that our customers receive a consistent and effective product every time they purchase from us.
3. Third-party testing: Our Wheat Germ Powder undergoes third-party testing to ensure that it meets the highest standards of quality and purity. This gives our customers the peace of mind that they are buying a safe and effective product.
4. Versatility: Wheat Germ Powder is a versatile natural ingredient that can be used in a variety of health and wellness products, including dietary supplements, functional foods, and personal care products. This makes it an attractive choice for manufacturers looking to create innovative and effective products.
5. Health benefits: Wheat Germ Powder has numerous health benefits, including its ability to act as an antioxidant, support heart health, and reduce the risk of certain types of cancer. This makes it an attractive choice for consumers looking for natural alternatives to synthetic medications.
Our Package
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| 1KG-5KG Inner Packing | 1KG-5KG Foil Bag Protection | 1KG-5KG Outer Packing | 25KG Outer Packing | 25KG Customized Outer Packaging |
Storage&Shelf Life
| Storage under room temperature, avoid heat and light. |
| 24 months from the manufacturing or testing date. |
Logistics Tips
| Express Way | Amount Request | Time Request | Main Advantage |
| DHL or FedEx | Under 100KG | 4-6 Days | Door-to-door service, easy to pick up |
| Air Shipping | 100-1000KG | 5-7 Days | Airport to-airport service, professional clearance broker needed |
| Sea Shipping | Over 300KG | Around 30 Days | Port-to-port service, professional clearance broker needed |

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| Business License | Commodity Inspection | HALAL | ISO220000 | KOSHER |
Our Factory
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Our Laboratory
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Our Exhibition
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Spermidine Powder Supplier And Manufacturer
Botanical Cube Inc. has been supplying standardized herbal extracts for over 16 years, guaranteeing high quality products, competitive prices and the best service! Botanical Cube Inc.'s standardized herbal extracts are available in powder,capsules, tablets, gummies and drinks for use in dietary supplements, cosmetics and personal care, animal nutrition, nutraceuticals, functional foods and beverages etc.
As a professional herbal extract manufacturer,we have successfully obtained EU&NOP ,USDA, Kosher, Halal, ISO9001, ISO22000, SGS,FDAand other quality system certifications.
How To Buy Spermidine Powder?
Just send email to sales@botanicalcube.com, or submit your requirement in bottom form, we are of service at any time!
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