Botanical Cube Inc. is one of the most professional manufacturers and suppliers of synephrine hcl powder in China, featured by quality products and good price. Please rest assured to wholesale bulk discount synephrine hcl powder from our factory.
Peak Performance with Premium Synephrine HCl Powder
Looking for a powerful, natural ingredient to elevate your product line? You've come to the right place. Our Synephrine HCl powder, also widely known as Bitter Orange Extract or Citrus Aurantium extract, is a cornerstone ingredient in the world of dietary supplements. It's a naturally occurring alkaloid, prized for its ability to support weight management, boost metabolism, and provide a clean energy lift without the jitters often associated with other stimulants. This makes it an incredibly popular and effective addition to fat burners, pre-workout supplements, and sports nutrition formulas.
The Science and Market Behind Synephrine
The appeal of synephrine lies in its unique mechanism. Sourced from the fruit of the Citrus aurantium tree, this compound works as a thermogenic agent, helping to increase the body's metabolic rate and energy expenditure. Unlike some other stimulants, it achieves this without causing a significant increase in heart rate or blood pressure, offering a smoother, more balanced experience. As consumers increasingly seek out plant-based solutions for their health and fitness goals, the demand for high-quality Synephrine HCl powder continues to grow, cementing its status as a must-have ingredient in the health and wellness market.
Our Advantage: Beyond a Commodity Product
We understand that your product is unique, and we can help you tailor the formulation-from particle size and solubility to precise concentration-to meet your specific needs.Furthermore, our OEM service is designed to be a true partnership. We leverage our extensive experience not only in manufacturing but also in product formulation and regulatory compliance. This means we can help you navigate the complex process of creating a market-ready product, from concept to a perfectly labeled bottle on the shelf. This comprehensive support, combined with a superior raw material, ensures that your final product will be distinct, effective, and fully compliant, giving you a significant competitive edge in the market.
Why our Synephrine Hcl Powder?
1. Product-Specific Superiority: Beyond Standard Purity
Our Synephrine HCl powder is not only of pharmaceutical grade but is specifically purified to a minimum of 99% purity. We achieve this through a proprietary, multi-stage extraction and crystallization process that meticulously removes unwanted compounds and ensures you're getting a superior concentration of the active p-synephrine isomer.
2. A True Partnership: Our OEM & R&D Advantage
For us, supplying a raw ingredient is only the first step. Our true value lies in our comprehensive OEM capabilities, designed to accelerate your product development and market entry. Our two decades of experience mean we've seen every challenge and can offer unparalleled support.
- Formulation Expertise
We don't just send you a specification sheet; we collaborate with your R&D team. Our experts can provide data-backed insights on optimal dosage, solubility, and best practices for incorporating our Synephrine HCl powder into your specific product format, whether it's capsules, tablets, or liquid formulations.
- Regulatory Confidence
Navigating compliance is a major pain point. We provide a complete and meticulously prepared documentation package with every order, including Certificates of Analysis (CoA), Safety Data Sheets (MSDS), and stability data. This streamlined support dramatically reduces your QC time and simplifies the regulatory approval process in key markets.

Synephrine HCL

Methylsynephrine HCL

Citrus Aurantium Frui
COA
| Item | Specification | Result | Method |
|---|---|---|---|
| Appearance | White crystalline powder | Conforms | Visual |
| Odor & Taste | Characteristic | Conforms | Organoleptic |
| Assay (Synephrine HCL) | ≥ 98.0% | 98.63% | HPLC |
| Loss on Drying | ≤ 1.0% | 0.34% | USP <731> |
| Residue on Ignition | ≤ 0.5% | 0.21% | USP <281> |
| Melting Point | 187°C–193°C | 190.2°C | USP <741> |
| Specific Rotation | +28.0° to +34.0° | +30.6° | USP <781S> |
| Heavy Metals | ≤ 10 ppm | <10 ppm | ICP-MS |
| Lead (Pb) | ≤ 1 ppm | <0.1 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | <0.1 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | <0.1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | <0.01 ppm | ICP-MS |
| Total Plate Count | ≤ 1,000 CFU/g | <100 CFU/g | USP <2021> |
| Yeast & Mold | ≤ 100 CFU/g | <10 CFU/g | USP <2021> |
| E. coli | Negative | Negative | USP <2022> |
| Salmonella | Negative | Negative | USP <2022> |
| Staphylococcus aureus | Negative | Negative | USP <2022> |
| Solvent Residue | Meet Eur. Pharm. Limit | Conforms | GC-MS |
| Particle Size | 100% pass 80 mesh | Conforms | Sieving |
| Bulk Density | 0.40–0.60 g/mL | 0.52 g/mL | Tapped Density Method |
Applications
1. Fat-Burning & Weight Management
Synephrine HCL enhances thermogenesis and lipolysis by stimulating β-3 adrenergic receptors, thereby promoting calorie expenditure and fat metabolism. It is widely used in weight loss formulations for this reason.
2. Energy & Focus Support
As a mild stimulant, Synephrine HCL can improve mental alertness and physical energy. Athletes and fitness enthusiasts often use it in pre-workout blends to boost endurance and concentration.
3. Digestive Health
Research suggests that Synephrine HCL can help improve gastrointestinal motility and relieve mild digestive discomfort, contributing to better overall digestive function.
Recommended Dosage
Typical daily dosage ranges from 50 mg to 100 mg, depending on user needs and tolerance levels.
Start with a low dose to assess individual tolerance.
Avoid combining with other stimulants (e.g., caffeine) unless under professional guidance.
Not recommended for pregnant or breastfeeding individuals or those with cardiovascular conditions.
Synephrine HCL is generally safe when used at appropriate doses. However, users should be aware of potential side effects, especially when combined with other stimulants:
1. Increased heart rate
2. Elevated blood pressure
3. Dizziness or headache
4. Irregular heartbeat
Consult a healthcare professional before use, particularly for individuals with heart-related health issues or those taking medications.
FAQs
1. How does it work?
Synephrine works by stimulating beta-3 adrenergic receptors, which are found primarily in fatty tissue. This action helps to increase metabolic rate and thermogenesis (the body's heat production), leading to a higher rate of calorie burning.
2. What are the common side effects?
When used within the recommended dosage, synephrine is generally well-tolerated. Some users may experience mild, dose-dependent side effects such as increased heart rate, anxiety, or jitteriness. For individuals sensitive to stimulants, it's best to start with a low dose.
3. Is Synephrine a stimulant like caffeine?
Yes, it is a stimulant, but its mechanism of action is different from caffeine. While caffeine works on the central nervous system, synephrine primarily affects the body's metabolic rate. This often results in a smoother, more sustained energy boost without the sharp "peak and crash" feeling associated with high caffeine intake.
4. Is it safe to combine with other ingredients?
Yes, synephrine is commonly combined with other synergistic ingredients in supplements, such as caffeine, green tea extract, L-carnitine, and yohimbine. However, caution should be taken when combining it with other strong stimulants, as this can increase the risk of side effects.
5. What is the difference between Synephrine HCl and Bitter Orange Extract?
Synephrine HCl is a highly purified and isolated compound. It is a standardized product with a consistent concentration of synephrine. Bitter Orange Extract, on the other hand, is the raw plant extract from the Citrus aurantium fruit. It contains varying amounts of synephrine along with other alkaloids and compounds, making it less precise in dosage and potency compared to the purified HCl form.
Trusted Synephrine HCL Bulk Supplier
We work closely with brands, contract manufacturers, and wholesalers to provide high-purity Synephrine HCL Powder with stable supply and reliable specifications. Whether you need bulk stock, OEM service, or a long-term supply partner, we're here to support your business. Contact us at sales@botanicalcube.com to discuss your needs.
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