Botanical Cube Inc. is one of the most professional manufacturers and suppliers of cholecalciferol powder in China, featured by quality products and good price. Please rest assured to wholesale bulk discount cholecalciferol powder from our factory.
Cholecalciferol powder, commonly known as vitamin D3, is a fat-soluble vitamin essential for calcium absorption, bone health, immune support and overall well-being. It is typically derived from lanolin (sheep wool fat) and is carefully processed into a fine, easy-flowing powder. It has a high IU potency and excellent stability after microencapsulation, making it ideal for tableting, premixes and powdered beverage systems.As the most bioavailable form of vitamin D, cholecalciferol plays a vital role in maintaining healthy blood calcium and phosphorus levels. Our highly purified cholecalciferol is formulated for flexibility, stability and proven functionality in dietary supplement, functional food and animal nutrition formulations.

Why choose our cholecalciferol powder?
1. High microencapsulation efficiency – over 95%
Our proprietary microencapsulation technology ensures uniform protection against oxidation, light and heat, ensuring the potency of the active ingredient is maintained during storage and processing.
2. Low residual solvents: < 0.005%
Our extraction process results in residual solvent levels below 0.005%, well above the USP and EP limits. This is critical for clean label and pharmaceutical grade applications.
3. Consistent particle size distribution: D90 ≤ 100μm
We precisely control particle size to ensure better mixing properties for premixes and uniformity for tablet or capsule formulations. Our D90 is below 100μm, which means excellent dispersibility in both water-dispersible and oil-based systems.
4. Custom IU Range: 100,000 IU/g to 2,000,000 IU/g
We offer custom IU concentrations based on your formulation needs. Whether it's for infant formula, vegan capsules or animal feed, we can adjust to your needs.
COA
| Item | Specification | Result | Test Method |
|---|---|---|---|
| Appearance | White to light yellow powder | Light yellow powder | Visual |
| Odor & Taste | Characteristic, no off-odor | Complies | Organoleptic |
| Identification | Positive for Cholecalciferol | Positive | HPLC |
| Assay (Vitamin D3 Content) | ≥500,000 IU/g | 512,000 IU/g | HPLC |
| Loss on Drying | ≤5.0% | 2.3% | USP <731> |
| Particle Size (D90) | ≤100μm | 83.6μm | Laser Diffraction |
| Heavy Metals | ≤10 ppm | <5 ppm | ICP-MS |
| Lead (Pb) | ≤2 ppm | 0.6 ppm | ICP-MS |
| Arsenic (As) | ≤1 ppm | 0.2 ppm | ICP-MS |
| Cadmium (Cd) | ≤1 ppm | 0.1 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | ND (Not Detected) | ICP-MS |
| Total Plate Count | ≤1,000 cfu/g | <100 cfu/g | USP <61> |
| Yeast & Mold | ≤100 cfu/g | <10 cfu/g | USP <61> |
| E. coli | Negative | Negative | USP <62> |
| Salmonella | Negative/25g | Negative | USP <62> |
| Residual Solvents | ≤0.005% | <0.002% | GC-MS |
| Stability (24 months) | Retains ≥90% IU | Ongoing | Real-time & Accelerated |
| Solubility | Dispersible in water | Complies | Internal Method |
| Encapsulation Rate | ≥95% | 96.2% | Internal Method |
What is cholecalciferol powder used for?
1. Dietary Supplements
– Capsules, tablets, softgels, gummies
2. Functional Foods & Beverages
– Fortified dairy alternatives, powdered drink mixes, nutrition bars
3. Infant & Maternal Nutrition
– Infant formula, prenatal vitamins
4. Animal Feed & Pet Nutrition
– Fortification in poultry, swine, and pet diets
5. Pharmaceuticals
– Prescription Vitamin D3 therapies for deficiency treatment
Recommended Dosage (General Guidelines)
Adults (General Nutrition): 600–2,000 IU/day
Infants/Children: 400–1,000 IU/day
Therapeutic Use (Doctor-supervised): 5,000–10,000 IU/day
Animal Feed (Per kg of feed):
Poultry: 2,000–4,000 IU
Swine: 1,500–3,000 IU
Pets: 300–800 IU
Note: Exact dosage depends on region, application, and regulations.
FAQs of cholecalciferol powder
1. Is cholecalciferol powder vegan?
Most cholecalciferol is extracted from lanolin and is therefore not a vegan product. However, we also offer a certified vegan vitamin D3 from lichen. We can provide both products upon request.
2. How do you use cholecalciferol powder in food or beverage products?
Use microencapsulated dosage form to improve water dispersibility and stability. Add at low temperature heating stage to avoid loss of potency. Mix with stabilizer to ensure uniform distribution.
3. What is the difference between vitamin D2 and D3?
D3 (cholecalciferol) is more bioavailable and more effective in increasing and maintaining serum 25(OH)D levels than D2 (ergocalciferol).
Whether you're formulating a nutritional supplement, functional food, or fortified feed, we're ready to support your goals with high-quality Cholecalciferol Powder. From bulk supply to customized OEM and ODM solutions, we help you bring your ideas to life with precision and reliability.Reach out to us at sales@botanicalcube.com - our team is here to respond quickly and work closely with you.
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