Sophora Flavescens Extract Matrine 98% Oxymatrine Powder

In order to improve product quality and economic benefits, technical improvement and innovation must be carried out. After in-depth analysis and research, we decided to apply the new technology to our Cranberry Fruit Powder, Wild Ginger Extract, Wolfberry Powder . Our products are designed with the end user in mind, ensuring maximum functionality and ease of use. With our expertise and vast network, we are able to provide affordable and efficient solutions. We now have a highly efficient crew to deal with inquiries from clients.

Matrine Powder is often evaluated by assay, but in real use, what matters more is how the material performs once it enters production.

At Botanical Cube, our Matrine Powder (Sophora flavescens extract / Ku Shen extract) is developed with a focus on consistency, usability, and formulation compatibility. Instead of simply increasing the Matrine percentage, we pay closer attention to alkaloid balance and particle structure, because these two factors directly influence how the extract behaves in capsules, tablets, and liquid systems.

This extract comes from the root of Sophora flavescens, and its activity is mainly driven by a group of compounds called quinolizidine alkaloids. Among them, Matrine is the primary component, while Oxymatrine plays an important supporting role, especially in how the material behaves in water-based systems.In real formulations, these compounds don't act in isolation. Their proportion influences not only the functional side, but also very practical aspects like taste, solubility, and stability. Keeping a balanced profile tends to make the extract easier to work with, particularly when it's part of a more complex formula.

This approach helps reduce common issues during scale-up-such as unstable flow, excessive bitterness, or inconsistent dispersion-so your team can move from sampling to production with fewer adjustments.

98% Matrine Powder (80Mesh)	98% Oxymatrine Powder(60Mesh)	20% Matrine Powder	Sophora flavescens root

1. Balanced active profile for real use
Instead of pushing extreme purity, we control the Matrine / Oxymatrine ratio (about 70:30–85:15), which makes the extract more stable and predictable in both liquid and solid formulations.

2. Less bitterness pressure in formulation
Bitterness is reduced by around 20–30% compared with standard Matrine powders, giving more room for dosage design without heavy masking systems.

3. More stable in production handling
Particle size is controlled at D90 ~80–120 μm, helping improve flow during encapsulation and tableting, with fewer issues like uneven filling or machine adjustment.

4. Better performance in liquid systems
Compared with typical materials, it shows slower sedimentation and more stable dispersion, which helps maintain appearance and consistency over shelf life.

When Matrine Powder moves beyond small-scale testing, several practical challenges can appear:

• Bitterness affecting final product acceptance
• Sedimentation or instability in liquid systems over time
• Inconsistent powder flow during encapsulation or tableting
• Variation in behavior between batches, even with similar specifications

These are typical formulation and production concerns, especially for extracts that are optimized mainly around assay values.

Our work on this ingredient is focused on making it easier to use in real formulations:

1. Controlled bitterness profile

Processed to reduce sharpness while maintaining functional strength, giving more flexibility in product design.

2. Balanced alkaloid composition
Managing the Matrine and Oxymatrine ratio to support both stability and compatibility across formats.

3. Optimized particle size for processing
Designed to improve flowability and reduce variation during encapsulation and compression.

4. Improved dispersion in liquid systems
Helping reduce visible sediment and improve overall appearance over shelf life.

Product Process

1. Skincare and Cosmetics

Commonly used in skincare formulations, as a Sophora flavescens root extract, it helps regulate sebum production, reduce acne, and improve skin barrier function. It has anti-inflammatory and soothing properties, making it suitable for sensitive skin and acne-prone skincare products.

2. Anti-Aging Products

As a natural antioxidant, it reduces free radical damage and delays the signs of aging.

It is often combined with other plant extracts in creams, serums, and masks.

3. Pharmaceuticals and Nutraceuticals

Used in supplements or traditional formulations, it has hepatoprotective, anti-inflammatory, and immunomodulatory properties.

It supports cardiovascular health by promoting blood circulation and protecting vascular endothelial cells.

4. Veterinary and Animal Health

Due to its antibacterial and antiparasitic properties, it can be added to feed formulations for poultry, aquaculture, and livestock.

1. Cosmetic Formulations
0.1% - 2.0%, depending on product type (cream, serum, toner).

2. Dietary Supplements
50 mg - 200 mg daily (standardized extract), always subject to approval by local regulatory authorities.

3. Animal Feed
100 mg - 500 mg/kg, depending on species and formulation.

1. Is matrine safe for skin?

Yes, within the recommended concentration range. Matrine is widely used in skincare and is an extract from the root of Sophora flavescens. It is well-tolerated and low-irritant.

2. What are the benefits of matrine powder in cosmetics?

It helps control oil, reduce acne, soothe inflammation, and provides antioxidant protection, making it suitable for anti-aging and anti-acne skincare.

3. Does matrine have antibacterial properties?

Yes, studies have shown it to have potent antibacterial and antiviral activity, making it suitable for use in skincare products as well as animal feed.

4. What is the difference between matrine and oxymatrine?

Both are alkaloids extracted from Sophora flavescens. Matrine focuses more on anti-inflammatory and skin-related benefits, while oxymatrine has stronger antiviral and liver-protective properties.

If you're already developing a Matrine Powder (Sophora flavescens / Ku Shen extract) product, the real challenge is usually not sourcing-it's getting the material to behave the same way when you scale up.That's exactly what this material is built for, and we can support both bulk supply and OEM development depending on your project needs.Contacat us at sales@botanicalcube.com.Send us your application details, and we'll come back with straightforward feedback on suitability, dosage range, and production fit.

100,000-class clean room	Huxian Factory	Shanyan Factory

UV test machine	Technbique Team	HPLC Test Machine

USDA Organic	EU Organic	HALAL	ISO220000	cGMP

Our efforts to improve the quality of our Sophora Flavescens Extract Matrine 98% Oxymatrine Powder and services will help us establish a positive image while increasing sales. We always think from the customer's point of view and provide products that are more in line with the customer's interests from a professional point of view. We want to create a rational, institutionalized, and humane working environment, seeking maximum profit sharing for employees, shareholders and customers.

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