Botanical Cube Inc. is one of the most professional manufacturers and suppliers of water-soluble black pepper extract powder in China, featured by quality products and good price. Please rest assured to wholesale bulk discount water-soluble black pepper extract powder from our factory.
What is black pepper extract powder?
Black pepper is used as a traditional herbal remedy for a variety of ailments and is one of the most important medicinal herbs to which the active ingredient piperine is the main contributor. Black pepper extract is made from the dried near-ripe or mature fruit of Piper nigrum with a black peel, which needs to be harvested in late autumn to the following spring when the fruit is dark green and dried in the sun.
We mainly use solvent extraction and our main product specifications are 10%-98%, with product colors ranging from pale yellow to off-white. The most common application is in combination with curcumin to improve its bioavailability.
The need for water-soluble black pepper extract powder?
Studies have shown that piperine, the active ingredient in black pepper extract powder, can increase the bioavailability of some components. For example, fat-soluble vitamins, coenzyme Q10, resveratrol, and curcumin. Piperine is chemically insoluble in water and soluble in organic solvents such as ethanol, which limits its effectiveness, so it is necessary to produce water-soluble black pepper extract.
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Name | Piperine | CAS No. | 94-62-2 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 498.5±40.0 °C at 760 mmHg | |
| Molecular Formula | C17H19NO3 | Melting Point | 131-135 °C(lit.) | |
| Flash Point | 255.3±27.3 °C |
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Why Botanical Cube's black pepper fruit extract?
Water-Soluble Black Pepper Extract Powder with 5% piperine is our special specification of black pepper extract. The nature of piperine itself cannot be dissolved in water. After accumulating some customer opinions, customers still have a strong demand for this aspect. So our technicians, after a series of experiments, finally developed this water-soluble piperine. If you have this Water-Soluble black pepper fruit extract requirement, you can contact us at sales@botanicalcube.com, it is a good try.
What is black pepper fruit extract good for?
1. Increasing Supplement/Drug Bioavailability
piperine powder become recognized in 1979 because of the first-ever compound ever that complements the "bioavailability" of different substances. In different words, piperine will increase the cap potential of the frame to apply vitamins and pills. This manner that decreases or fewer doses of the drug may be used to gain an equal effect. This could be very useful in terms of pills that have ugly aspect effects!
2. Antioxidant
piperine powder might also additionally defend against oxidative strain by disposing of unfastened radicals (consisting of hydroxyl and superoxide) from the frame. In a small trial on 20 humans with pancreatitis, an aggregate of curcumin (500 mg) and piperine (five mg) stepped forward their antioxidant reputation (decrease fats peroxidation and MDA and better glutathione degrees). Combinations with an equal share of curcumin and piperine additionally stepped forward antioxidant reputation in three trials on over one hundred humans with metabolic syndrome, nearly one hundred humans with continual lung disease, and forty humans with osteoarthritis.
3. Inflammation
In a scientific trial on over one hundred humans with kind 2 diabetes or metabolic syndrome, an aggregate of curcumin and piperine had anti-inflammatory effects (measured as decreased CRP degrees). However, the combination turned contained 100x greater curcumin than piperine. A comparable blend additionally decreased infection (decreased degrees of IL4, IL-6, and CRP) in a scientific trial on forty humans with knee osteoarthritis. Piperine decreased short- and long-time period signs of infection in rats.
4. Metabolic Syndrome
As formerly mentioned, the aggregate of curcumin (1,000 mg/day) and piperine powder (10 mg/day) stepped forward oxidative, inflammatory, and blood fats reputation in 2 scientific trials on over 2 hundred humans.
5. Lowering Blood Sugar
In a scientific trial on one hundred humans with kind 2 diabetes, an aggregate of 500 mg/day of curcumin and five mg/day of piperine diminished blood sugar and decreased liver damage. In diabetic mice, a low dose of piperine (20 mg/kg frame weight) decreased blood sugar. However, better doses expanded blood sugar degrees.
7. Cognitive Function
Multiple animal research endorses that piperine can increase mental features.
8. Depression
Piperine black pepper extract had antidepressant outcomes in mice subjected to persistent stress. This impact became related to the extended manufacturing of the latest mind cells and extended BDNF ranges withinside the hippocampus. Depression is not unusual to place in epilepsy. In rats with epilepsy, nutritional piperine decreased signs of melancholy via way of means of growing serotonin ranges.
9. Parkinson's Disease
In mice with Parkinson's disease, piperine advanced motor coordination. It additionally advanced mind features and learning. Increasing dopamine ranges is the maximum not unusual place manner to deal with Parkinson's disease. Piperine inhibits MAO-A and MAO-B, the enzymes that spoil down dopamine, probably growing universal dopamine range withinside the mind. Piperine additionally averted the loss of life of dopamine neurons in mice. It blanketed neurons due to the fact it's miles an antioxidant, is anti-inflammatory, and stops the programmed molecular loss of life.
10. Allergies
Piperine reduces irritation and suppresses the immune system, making it an amazing candidate for treating and stopping allergies. In mice, piperine reduces sneezing, nose-rubbing, and different signs of allergies. It dose-dependently reduced histamine, nitric oxide, IgE, and inflammatory cytokines IL-6 and IL-1b.
11. Pain
As little as five milligrams of piperine in keeping with a kilogram of frame weight decreased aches in mice and rats. In humans, this will be more or less equal to 1/sixth of a teaspoon. Another look at mice confirmed that better doses, around 30 to 70 mg in keeping with kg frame weight, had a comparable impact, an ache-relieving drug just like aspirin or ibuprofen.
13. Lowering Blood Pressure
Piperine brought on a large drop in common blood strain while fed to rats. In some others have a look at rats, it became capable of partly saving you the boom in blood strain because of a drug (NOS inhibitor).
15. Diarrhea
Piperine averted diarrhea in mice. In rabbits and guinea pigs, it labored in addition to loperamide, some other drug used to deal with diarrhea – however without inflicting any of loperamide's standard aspect outcomes.
What are Water-Soluble Black pepper extract applications?
1. As a raw material for arthritis, rheumatism, anti-inflammatory, swelling, and other drugs, it is mainly used in the pharmaceutical field.
2. As an active ingredient in products to improve blood circulation and soothe the nerves, it is mainly used in the health care product industry.
3. As an active ingredient in skincare products, it is mainly used in the cosmetic industry.
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Step1 Raw Material Picking |
Step2 Solvent Extraction |
Step3 Extracts Concentration |
Step4 Crystallization and Drying |
Step5 Testing and Packing |
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| Select and clean raw materials, and crush them into pieces. | Choose the proper extraction solvent and extract it several times. | Put the extracted liquid into the concentration machine until the liquid change to a paste state. | Crystallization is for high purity. Drying for high-temperature spray drying. | Packing in the 100,000 class purification workshop. Testing for twice before and after packing. |
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| Product Chromatogram | Heavy Metal Report | Microbiology Report | ETO Report | PAH Report |
Our Package
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| Inner Packing | Foil Bag Protection | 1KG-5KG Outer Packing | 25KG Outer Packing | 25KG Customized Outer Packaging |
Ship and Delivery
Transit could be DHL, UPS, TNT, FEDEX, or EMS. For mass orders, it will be delivered by air or sea.
FAQ
| Q1: How do you ensure the quality of your products? |
| A1: Strict QC with 6 steps of testing from raw material purchase to finished product. |
| Q2: What about your standard delivery time? |
| A2: For sample orders less than 25kgs, the delivery is within 3 days. For bulk orders normally the delivery time is 7-10 days. For urgent orders please kindly double-check with our sales before orders are confirmed. |
| Q3: Is there any discount? |
| A3: Sure, Prices are closely related to the quantity. The more, the cheaper. |
| Q4: Can you provide samples? |
| A4: Yes, normally we can provide FREE samples of 5-20 g based on shipping cost at the customer's account. |
| Q5: Do you have a guarantee on your products? |
| A5: The product is 100% pure natural with high quality. We are sure that every batch comes with a unique COA. All extracts are tested in-house; random extracts are tested by authoritative analytical labs. |
| Q6: What is your MOQ? |
| A6: For most of the products, the MOQ is 1kg. But for some of the products we can accept less quantity such as 100g. |
| Q7: What are your payment terms? |
| A7: Payment terms such as T/T, Visa Card, Master Card, e-Checking, Paypal, and Western Union. |
| Q8: How to ship and deliver? |
| A8: For sample orders, we always ship via express such as DHL, UPS, TNT, FEDEX, and EMS. For bulk orders, air or sea shipment is common. |
| Q9: Can you supply OEM or ODM service? |
| A9: For sure as is known Botanical Cube is especially on producing herb extract; OEM tablets, capsules, and small packing. For Sure we are the best partner for OEM&ODM suppliers. |
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| Business License | Commodity Inspection | HALAL | ISO220000 | KOSHER |
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We always pay attention to the continuous development of plant extract powder such as Fructus Cnidii Powder and strive to become the industry leader and provide customers with the most cost-effective and practical products. We look forward to leading the continuous development of technology and products with an innovative spirit, responding to new customer needs, and promoting the prosperity and progress of society. The products are sold in Europe, America, Southeast Asia, and other regions, and are widely praised by users. Welcome to contact us at sales@botanicalcube.com
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