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PDRN Powder for Skincare & Personal Care
PDRN Powder (Polydeoxyribonucleotide / Sodium DNA) is a water-soluble DNA-derived cosmetic ingredient supplied as a fine powder for modern skincare and personal care formulations. It can be used in serums, ampoules, creams, masks and scalp care products where a PDRN-based active is required.
With defined purity specifications, analytical testing and batch-specific COA, Botanical Cube supports PDRN sourcing from formulation testing to commercial scale-up. Samples, technical specifications and customized supply options are available for product development and bulk purchasing.
What to Check When Sourcing PDRN Powder
PDRN is a DNA-derived cosmetic ingredient commonly supplied as Sodium DNA. For formulation and raw material sourcing, the key differences between PDRN products are not only the stated purity, but also the source, molecular-weight profile, solubility, pH and supporting analytical data.These parameters help formulators and buyers determine whether a PDRN grade is suitable for their formulation and quality requirements.
* Agarose Gel Electrophoresis: PDRN Molecular Weight Screening
Why Our PDRN Powder Fits Formulation Needs
1. Defined PDRN Content
Clear specification with batch-specific COA for purity and consistency verification.
2. Controlled Molecular Weight
Molecular-weight data supports grade comparison and formulation development.
3. Water-Soluble Powder
Easy to incorporate into serums, ampoules, creams, masks and other water-based formulations.
4. Clear Source & Technical Data
Source, pH, solubility and analytical data are available to support formulation evaluation and raw material sourcing.
COA
| Test Item | Specification | Test Result | Test Method |
|---|---|---|---|
| Appearance | Off‑white to light gray‑white powder | Off‑white to light gray‑white powder | Visual inspection |
| Odor | Characteristic slight fish‑like odor, no peculiar smell | Complies | Sensory evaluation |
| Solubility | Soluble in water, clear or slightly opalescent aqueous solution | Soluble in water, slightly opalescent solution | Visual observation (1% w/w water solution) |
| pH value (1% Aqueous Solution) | 5.0‑9.0 | 6.4 | pH meter |
| Loss on Drying | ≤8.0 % | 4.2 % | Vacuum drying method |
| Molecular Weight | ＜650 KDa / ＜1050 bp | 520‑610 KDa / 820‑980 bp | Gel Electrophoresis |
| Assay (HPLC, wt%) | ≥95.0 % | 97.3 % | High‑Performance Liquid Chromatography |
| Heavy Metal‑Arsenic (As) | ≤2 ppm | 0.7 ppm | ICP‑MS |
| Heavy Metal‑Lead (Pb) | ≤10 ppm | 2.1 ppm | ICP‑MS |
| Heavy Metal‑Cadmium (Cd) | ≤1 ppm | ＜0.1 ppm | ICP‑MS |
| Heavy Metal‑Mercury (Hg) | ≤1 ppm | ＜0.1 ppm | ICP‑MS |
| Total Aerobic Bacteria Count | ≤100 CFU/g | 12 CFU/g | Microbiological plating method |
| Yeast & Molds | ≤10 CFU/g | ＜10 CFU/g | Microbiological plating method |
| Escherichia coli (E.coli) | Not detected / g | Not detected | Microbiology test |
| Staphylococcus aureus | Not detected / g | Not detected | Microbiology test |
| Pseudomonas aeruginosa | Not detected / g | Not detected | Microbiology test |
| Salmonella spp. | Not detected / 10g | Not detected | Microbiology test |
| Endotoxin | ≤10 EU/mg | 3.6 EU/mg | LAL test |
| Protein Residue | ≤1.0 % | 0.41 % | BCA protein assay |
| Nucleic Acid Impurity | ≤2.0 % | 0.83 % | UV spectrophotometry |
PDRN Production Flow :
Key Applications of PDRN Powder
1. Serums & Ampoules
Concentrated skincare formulas where PDRN is used as an active cosmetic ingredient.
2. Creams & Lotions
Daily skincare and skin-conditioning formulations.
3. Facial Masks
Sheet masks, gel masks and other leave-on mask products.
4. Eye Care
Eye serums and creams for targeted skincare formulations.
5. Scalp & Hair Care
Scalp serums and hair-care formulations incorporating PDRN.
PDRN Powder Formulation
PDRN Powder is water-soluble and suitable for water-based skincare formulations. When developing a formula, it is useful to check not only solubility, but also molecular weight, solution appearance and pH.
1. Water Solubility
Suitable for serums, ampoules, creams, masks and other water-based formulas.
2. Molecular Weight
An important specification when comparing different PDRN grades for formulation use.
3. pH & Solution Appearance
Check the pH and appearance of the PDRN solution under the intended formulation conditions.
4. Sample & Technical Documents
Botanical Cube provides samples, product specifications and batch-specific COA for formulation testing before bulk purchasing.
| Ingredient | Common Combination | Typical Applications | Key Considerations |
|---|---|---|---|
| Hyaluronic Acid | Sodium Hyaluronate | Serums, Ampoules, Essences | Check pH and viscosity |
| Peptides | GHK-Cu, Signal Peptides | Serums, Ampoules | Check pH and ingredient compatibility |
| Niacinamide | Niacinamide | Serums, Creams, Lotions | Check final formulation pH |
| Panthenol | D-Panthenol | Serums, Masks, Lotions | Suitable for water-based formulations |
FAQs
1. What PDRN specifications are important for cosmetic formulation?
Key parameters include PDRN content, molecular weight, pH, solubility and solution appearance. These specifications help formulators compare different PDRN grades and select the appropriate raw material.
2. Why is molecular weight important when comparing PDRN?
Molecular weight is a key specification for distinguishing different PDRN grades. It should be evaluated together with the product's assay, solubility and intended formulation system.
3. What should be checked when adding PDRN to a formulation?
Check dissolution, pH, heat exposure and compatibility with other actives, preservatives and the finished formulation. A small-scale stability and compatibility test is recommended before scale-up.
4. Can Botanical Cube provide batch-specific quality documentation?
Yes. Batch-specific COA and product specifications can be provided for quality review, formulation testing and commercial sourcing.
5. Can the PDRN specification be customized?
Yes. Specification requirements can be discussed according to the formulation, target application and purchasing requirements. Sample evaluation can be arranged before commercial orders.
Request PDRN Powder Sample & COA
For a PDRN formulation or sourcing project, send us your required specification, application and quantity. We can provide the relevant PDRN Powder specification, batch-specific COA and sample for your formulation and quality evaluation.
If your project has specific requirements for PDRN content, molecular weight, pH or other quality parameters, please include them in your inquiry. Our team can check the available specification and supply accordingly.Contact us at sales@botanicalcube.com.
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