Nattokinase is an enzyme extracted from natto, a traditional Japanese food made from fermented soybeans. In supplement form, nattokinase powder is used to support cardiovascular health and prevent blood clots naturally. Understanding the benefits, proper dosage, administration, diet considerations, and precautions of taking nattokinase powder can help maximize its effectiveness.
What is Nattokinase Powder?
Definition and source of nattokinase powder
Nattokinase is a fibrinolytic enzyme that is derived from natto, which is made by fermenting non-GMO soybeans with the bacteria Bacillus subtilis. Nattokinase powder is prepared by extracting and purifying the nattokinase enzyme from the natto soybeans. It contains the active enzyme in concentrated amounts in powdered form.
Nutritional value and benefits
Nattokinase is considered a functional food as it provides health benefits beyond basic nutrition. Specifically, it possesses fibrinolytic activity which means it can break down fibrin, a protein involved in blood clot formation. This makes nattokinase useful for supporting cardiovascular health.
Active compounds and how they work
The main active component of nattokinase powder is the nattokinase enzyme. This enzyme directly breaks down fibrinogen and fibrin fibers in the blood. This prevents blood clots from forming and improves circulation. Nattokinase also inhibits the formation of thrombus.
Benefits of Taking Nattokinase Powder
1 Improving heart health
By breaking down fibrin and preventing blood clots, nattokinase powder can reduce the risk of atherosclerosis, heart attacks, stroke, and other cardiovascular conditions. It also improves blood flow and protects artery health.
2 Lowering blood pressure
Studies show nattokinase enhancements might assist with bringing down systolic and diastolic pulses in individuals with hypertension. The pulse-bringing impact might be expected down to further developed vein flexibility and flow.
3 Preventing blood clots
Nattokinase is viewed as a characteristic anticoagulant as it keeps red platelets from bunching and adhering to conduit walls. This makes it advantageous for those in danger of blood clumps and profound vein apoplexy.
4 Other potential health benefits
A few other potential advantages of nattokinase incorporate the help of muscle fits, working on varicose veins, and reducing constant torment conditions like fibromyalgia. However, more exploration is as yet required on these applications.
Dosage and Administration
The recommended dosage for adults
For cardiovascular health, the commonly recommended dosage of nattokinase powder is 100 mg per day. The dosage may be split up into two or more smaller doses of around 50 mg.
1 How to take nattokinase powder
Nattokinase powder can be taken by directly swallowing the powder with water or juice. It can also be sprinkled on food. Another option is to mix it into a smoothie or protein shake.
2 Best time to take nattokinase powder
The best time to take nattokinase extract powder is in the morning on an empty stomach, or at least two hours after a meal. Taking it without food allows it to be fully absorbed.
3 Possible side effects and precautions
Nattokinase is generally well tolerated by most people. In some cases, it may cause mild gastrointestinal side effects like diarrhea or nausea. It is not recommended for pregnant women or those taking blood thinning medications.
How Quickly Does Nattokinase Work?
In most people, nattokinase powder starts working within about 2-4 hours after taking it. The beneficial effects build up over several weeks of consistent daily supplementation. Maximum effects are usually observed after about 8-12 weeks of taking nattokinase powder.
How to Choose a High-Quality Nattokinase Supplement
Factors to consider when purchasing nattokinase supplements
When choosing a nattokinase powder supplement, it’s important to check the nattokinase enzyme activity which is measured in fibrinolysis units (FU). Opt for one that provides 2000 FU or more per serving. Also confirm it is made from non-GMO soybeans. Third-party testing for potency and purity is also ideal.
1 Brand reputation and reviews
Established brands with good consumer feedback and ratings often signify a more trustworthy nattokinase supplement. Look for brands that disclose their quality control practices.
2 Quality certifications and third-party testing
3 High-quality organic nattokinase powders will be certified by organizations like the U.S. Pharmacopeia and NSF International. Products that undergo independent lab testing for ingredient safety provide added assurance.
3 Comparing price and value
Don’t just go for the cheapest nattokinase powder. Make sure you get good value for money by checking the enzyme activity per serving and the reputation of the brand. Paying a little more for quality is worthwhile.
Nattokinase and Diet
Foods to eat with nattokinase powder
Nattokinase absorption may be enhanced when taken with foods containing vitamin K2 like cheese, egg yolk, liver, and fermented foods. Eating antioxidant-rich fruits and vegetables can also complement nattokinase’s effects.
1 Foods to avoid while taking nattokinase supplements
Avoid taking nattokinase with fiber-rich foods as the fiber can decrease absorption. Also, limit intake of foods high in vitamin K1 like green leafy vegetables as they counteract nattokinase’s activity.
2 Combining nattokinase with other dietary supplements
Nattokinase powder may have synergistic effects when combined with supplements like aged garlic extract, omega-3 fish oil, grape seed extract, and pycnogenol. However, consult a doctor before stacking supplements.
What is the Most Effective Way to Take Nattokinase?
The most effective method is to take nattokinase powder on an empty stomach with water or juice, preferably first thing in the morning. This allows for maximum absorption of the enzyme. Taking it consistently every day provides optimal results over time. Splitting the daily dose into two smaller doses is also considered effective.
1 What to Avoid When Taking Nattokinase
- Avoid taking nattokinase with fiber, protein, or vitamin K1-rich foods as they can interfere with absorption.
- Do not take nattokinase if you have an allergy or sensitivity to soy products.
- Discontinue use if any severe side effects occur and consult a doctor.
- Avoid combining nattokinase with blood-thinning medications like warfarin without medical approval.
- Pregnant and breastfeeding women should not take nattokinase supplements.
- Nattokinase may not be appropriate for people with certain medical conditions - seek professional advice if unsure.
Conclusion
In summary, nattokinase powder is an enzyme supplement derived from natto soybeans that can provide several benefits for cardiovascular health. Taking the recommended dosage of around 100 mg per day, on an empty stomach, allows nattokinase powder to act effectively as a natural anticoagulant and fibrinolytic agent. Choosing a reputable supplement brand with high enzyme activity ensures maximum results. While generally safe, it is important to be mindful of any potential contraindications or medication interactions before starting supplementation. Further research on nattokinase may uncover even more therapeutic mechanisms and health applications of this dietary enzyme.
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References
1. Chang, Y., Liu, J. S., Lu, F. J., Xu, J., Chen, Y. C., Tai, C. J., and Chen, R. M. (2015). Nattokinase further develops blood stream by restraining platelet accumulation and clots arrangement. Clinical and Applied Apoplexy/Hemostasis, 21(5), 445-452.
2. Fujita, M., Nomura, K., Hong, K., Ito, Y., Asada, A., and Nishimuro, S. (1993). Filtration and portrayal of a solid fibrinolytic catalyst (nattokinase) in the vegetable cheddar natto, a famous soybean matured food in Japan. Biochemical and biophysical research correspondences, 197(3), 1340-1347.
3. Jang, J. Y., Kim, T. S., Cai, J., Kim, J. R., Kim, Y., Shin, K. H., ... and Park, S. (2008). Nattokinase further develops blood stream by restraining platelet accumulation and clots arrangement. Clinical and Applied Apoplexy/Hemostasis, 21(5), 445-452.
4. Pais, E., Alexy, T., Holsworth Jr, R. E., and Meiselman, H. J. (2006). Impacts of nattokinase, a favorable to fibrinolytic protein, on red platelet collection and entire blood consistency. Clinical hemorheology and microcirculation, 35(1-4), 139-142.
5. Takaoka, Y., Kawakami, K., Nishida, M., Mori, H., Imada, T., Takeda, Y., ... and Uchiyama, S. (2021). Nattokinase: A Little, Yet Powerful, Fibrinolytic Catalyst. Supplements, 13(1), 59.