Piperine is a natural active substance in black pepper. Pepper is considered the "king of spices", and its pungent smell mainly comes from piperine. Various experimental results show that piperine can help other nutrients increase their bioavailability when taken together.
▲What is bioavailability?
Bioavailability is an important indicator of the degree of absorption and utilization of drugs or nutrients by the body. Piperine can enhance the permeability of the small intestinal epithelial cell membrane to enhance the absorption of nutrients such as Q10 in the small intestine. In addition, it can inhibit glucuronyl transferase (UGT) to reduce the excretion of nutrients, thereby increasing the bioavailability of other nutrients.
▲Piperine can increase the bioavailability of those nutrients and drugs
We have sorted out some nutrients and drugs and piperine compounding through the literature to promote the increase of its bioavailability for your reference.
| Piperine | Name | Improve Bioavailability (%) | References |
 | Curcumin | 2000% | Planta Med. 1998 May;64(4):353-6 |
| Buddleoside | 381% | Molecules. 2014 Apr 30;19(5):5624-33 | |
| Vasicine | 233% | J Ethnopharmacol. 1981 Sep;4(2):229-32 | |
| Resveratrol | 229% | Mol Nutr Food Res. 2011 Aug;55(8):1169-76 | |
| Ginsenoside | 197% | Chin J Nat Med. 2018 Feb;16(2):143-149 | |
| Ubiquinone | 40% | J Nutr Biochem. 2000 Feb;11(2):109-13 |
The following video shows the product status and some attributes of our regular black pepper extract with piperine powder. We have sufficient inventory, the products in stock can ensure the quality, if your quantity is large, there will be relevant discounts. If you have any demand for this product, you are welcome to consult us at sales@botanicalcube.com