Botanical Cube Inc. is one of the most professional manufacturers and suppliers of cissus quadrangularis extract in China, featured by quality products and good price. Please rest assured to wholesale bulk discount cissus quadrangularis extract from our factory.
Cissus quadrangularis extract, also known as Veldt grape extract or osteotin, is a powerful herbal supplement derived from the Cissus quadrangularis plant that is widely used for its benefits for joint and bone health. The extract is rich in key bioactive compounds, including ketosterones and flavonoids, which are known to boost collagen synthesis, promote bone regeneration, and relieve joint pain. Due to these properties, it is often used in products targeting joint health, bone healing, and weight management.
In the current market,it's becoming increasingly popular for its natural anti-inflammatory and accelerated tissue repair properties, making it a preferred ingredient for dietary supplements and functional foods.At Botanical Cube, we take a rigorous approach to sourcing and manufacturing. We ensure that our extracts are sourced from premium, organically grown plants, providing a pure, concentrated formula with high levels of active ingredients. We also offer OEM services for it, providing customized solutions to meet our customers' specific needs. Whether you require bulk production or custom formulations, we can work with you to develop products that meet the unique needs of your brand.
Why choose our Cissus Quadrangularis Extract?
1. Standardized active ingredients
We guarantee a consistent total ketone content of around 40% and verify it batch by batch using a validated UV detection method, which ensures consistency in the efficacy of your final product.
2. Clean source
Our Cissus chinensis extract comes directly from certified farms in India, where the plant grows naturally. We do not mix sources or substitute varieties. Each batch is traceable to its growing region, and our raw materials are non-GMO, pesticide-free, and meet EU and US market access requirements.
3. Very low residue and solvent-free processing
We use a water-ethanol co-extraction process with low-temperature vacuum drying to ensure that the solvent residue is less than 100ppm, far below the EU Pharmacopoeia limit, while retaining sensitive plant active ingredients.
4. OEM-ready: From powder to capsules, one-stop service
We are not just a raw material supplier, but a full-service solution provider. With nearly 20 years of production and formulation experience, we provide OEM/ODM partners with full support from raw materials to finished products.
Services include:
Capsules/tablets/mixed formulations
Customized ketone-to-ketone ratio adjustment
Private brand design and compliance document support
COA
| Item | Specification | Result | Test Method |
|---|---|---|---|
| Appearance | Fine Powder | Conforms | Visual |
| Color | Yellow-Brown | Conforms | Visual |
| Odor & Taste | Characteristic | Conforms | Organoleptic |
| Mesh Size | 95% pass 80 mesh | Conforms | USP <786> |
| Loss on Drying | ≤5.0% | 3.12% | USP <731> |
| Ash | ≤5.0% | 2.65% | USP <561> |
| Active Ingredient | ≥40% Total Ketosterones (UV) | 41.3% | UV |
| Bulk Density | 0.45–0.65 g/mL | 0.57 g/mL | USP <616> |
| Tap Density | 0.60–0.80 g/mL | 0.72 g/mL | USP <616> |
| Heavy Metals | ≤10 ppm | <5 ppm | ICP-MS |
| Arsenic (As) | ≤2.0 ppm | <1.0 ppm | ICP-MS |
| Lead (Pb) | ≤3.0 ppm | <1.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | <0.2 ppm | ICP-MS |
| Mercury (Hg) | ≤0.1 ppm | <0.05 ppm | ICP-MS |
| Residual Solvent (Ethanol) | ≤5000 ppm | <100 ppm | GC-MS |
| Microbiological Analysis | |||
| Total Plate Count | ≤1,000 CFU/g | 230 CFU/g | USP <61> |
| Yeast & Mold | ≤100 CFU/g | <10 CFU/g | USP <61> |
| E. coli | Negative/10g | Negative | USP <62> |
| Salmonella | Negative/25g | Negative | USP <62> |
| Staphylococcus aureus | Negative/10g | Negative | USP <62> |
| Non-GMO | Compliant | Complies | In-house |
| Gluten | Not Detected | Not Detected | ELISA |
| Irradiation | Non-irradiated | Complies | In-house |
What is the use of Cissus quadrangularis extract?
1. Joint and Bone Health
Widely used in supplements to support cartilage regeneration, reduce joint inflammation, and promote faster recovery from bone fractures.
2. Sports Recovery Formulas
Incorporated in products targeting athletes and active individuals for muscle repair, injury prevention, and post-exercise recovery.
3. Weight Management Support
Sometimes included in metabolic support blends due to its potential to help regulate cortisol and reduce abdominal fat accumulation.
4. Anti-Inflammatory Support
Used in both oral and topical applications to combat oxidative stress and reduce systemic inflammation.
5. Men's Health Supplements
Occasionally added to formulas aimed at improving testosterone balance and bone strength in aging male consumers.
Recommended Dosage
1. Oral Supplements:
300–1,000 mg/day standardized extract (typically 2–3 times per day depending on formulation strength and concentration).
Clinical studies often use 500 mg twice daily of a 5% ketosterones extract.
2. Topical Use:
Generally formulated into creams or gels at concentrations of 2–5%, depending on the base material.
Note: Always follow dosage recommendations provided by formulators or healthcare professionals for final product design.
FAQs
1. Can Cissus Quadrangularis aid in weight loss?
Some studies suggest it can support fat metabolism and cortisol regulation, contributing to modest weight control effects, especially in overweight individuals.
2. How is Cissus Quadrangularis different from glucosamine or MSM?
Unlike glucosamine (which builds cartilage) or MSM (anti-inflammatory), Cissus also helps in bone regeneration and has antioxidant properties - making it multifunctional in joint/bone health.
3. Does it interact with other medications?
There is limited data on drug interactions. Clients formulating with this extract should consult toxicity studies or work with specialists when combining it with pharmaceuticals.
Cissus Extract Bulk Supplier OEM
If you're sourcing a reliable Cissus Quadrangularis Extract manufacturer or looking to customize your own formulation, we're ready to be your trusted partner. Backed by nearly 20 years of experience in plant extract production and OEM/ODM solutions, we offer stable supply, flexible packaging, and batch-to-batch consistency. Our extract is standardized, tested for key actives, and supported by certifications including ISO22000, HALAL, KOSHER, ORGANIC (EU & USDA), FSSC22000, and cGMP. What sets us apart is our in-house control from raw material to finished extract, ensuring quality that meets the standards of global nutraceutical brands. Let's discuss your next project - reach us at sales@botanicalcube.com.
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