The most active ingredients in ginger are the pungent principles, particularly gingerols and shogaols. Various preclinical and clinical studies have evaluated ginger as an effective and safe treatment for nausea and vomiting in the context of pregnancy and as an adjuvant treatment for chemotherapy-induced nausea and vomiting.
Ginger extracts accelerate gastric emptying and stimulate gastric antral contractions.These effects are mainly due to the presence of gingerols and shogaols and their activity on cholinergic M receptors and serotonergic 5-HT and 5-HT receptors.One study assessed the efficacy of ginger against the anti-histaminic drug dimenhydrinate and found ginger to be just as effective, with fewer side effects.
The article quoted from The Effectiveness of Ginger in the Prevention of Nausea and Vomiting during Pregnancy and Chemotherapy